Ref ID:	35069
Ref Type:	Journal Article
Authors:	Vimokesant, S. L. Hilker, D. M. Nakornchai, S. Rungruangsak, K. Dhanamitta, S.
Title:	Effects of betel nut and fermented fish on the thiamin status of northeastern Thais
Date:	1975
Source:	American Journal of Clinical Nutrition
Abstract:	Thiamin deficiency could result either from inadequate intake of thiamin or consumption of food containing antithiamin factors. Dietary surveys conducted in northeastern Thailand indicated that both thiamin and caloric intake of subjects under studies were sufficient. In Thailand, correlation exists between the consumption of food containing antithiamin factors and the prevalence of thiamin deficiency. Betel nuts and raw fermented fish possess antithiamin activity. Abstention from both betel nut chewing and raw fermented fish consumption resulted in a significant reduction of thiamin pyrophosphate effect. The thiamin pyrophosphate effect again increased significantly when the subjects resume their chewing habits. Coing of fermented fish destroyed thiaminase, resulted in a significant decrease of thiamin pyrophosphate effect of the subjects. Thiamin supplementation (10 mg/day) could further reduce their thiamin pyrophosphate effect. This amount of thiamin could counteract the effect of raw fermented fish consumption but was not sufficient to neutralize the effect of betel nut chewing.
Date Created:	6/28/2001
Volume:	28
Number:	12
Page Start:	1458
Page End:	1463