Ref ID:	35101
Ref Type:	Journal Article
Authors:	Panigrahi, G. B. Rao, A. R.
Title:	Induction of in vivo sister chromatid exchanges by arecaidine, a betel nut alkaloid, in mouse bone-marrow cells
Date:	1984
Source:	Cancer Letters
Abstract:	The genotoxicity of arecaidine, an alkaloid of betel nut, was studied on mouse bone marrow cells in vivo by sister chromatid exchange (SCE) method. Arecaidine was administered intraperitoneally to mice at the dose levels of 2.5 mg, 5 mg and 7.5 mg to each mouse weighing 25 +/- 1 g for 5, 10 and 15 days. Significant increase in the number of SCEs was observed in the treated groups, and this increase, although dose dependent, was not dependent upon the duration of exposure. PMID- 6744244
Date Created:	6/28/2001
Volume:	23
Number:	2
Page Start:	189
Page End:	192