Ref ID:	35130
Ref Type:	Journal Article
Authors:	Scutt, A. Meghji, S. Canniff, J. P. Harvey, W.
Title:	Stabilisation of collagen by betel nut polyphenols as a mechanism in oral submucous fibrosis
Date:	1987
Source:	Experientia
Abstract:	Treatment of reconstituted collagen fibrils and pieces of rat dermis with the crude extract, purified tannins or (+)-catechin from betel nut (Areca catechu) increases their resistance to both human and bacterial collagenases in a concentration-dependent manner. These tanning agents may stabilise collagen in vivo following damage to the oral epithelium and promote the sub-epithelial fibrosis which occurs in betel nut chewers. PMID- 3032668
Date Created:	6/28/2001
Volume:	43
Number:	4
Page Start:	391
Page End:	393