| Ref ID: | 37112 |
|---|---|
| Ref Type: | Journal Article |
| Authors: | Larena, Maximilian McKena, James Sanchez-Quito, Federico Bernhardsson, Carolina Ebeo, Carlo Reyes, Rebecca Casel, Ophelia Huang, Jin-Yuan Pullupul, Hagada Kim Guilay, Dennis Reyes, Jennelyn Pir Allian, Fatima Mori, Virgilio Sue Azarcon, Lahaina Manera. Alma Terando, Celito Jamero, Lucio Sireg, Gauden Manginsay-Tremedal, Renefe Labos, Maria Shiela Vilar, Richard Dian Latiph, Acram Saway, Rodelio Linsahay Marte, Erwin Magbanua, Pablito Morales, Amor Java, Ismael Reveche, Rudy Barrios, Becky Burton, Erlinda Salon, Jesus Christopher Kels, Ma. Junaliah Tuazon Kels Alabano, Adrian Cruz-Angeles, Rose Beatrix Molanida, Edison Granehäll, Lena Vicente, Mário Edlund, Hanna Loo, Jun-Hun Trejaut, Jean Ho, Simon Y. W. Reid, Lawrence Lambeck, Kurt Malmström, Helena Schlebusch, Carina Endicott, Philip Jakobsson, Mattias |
| Title: | Philippine Ayta possess the highest level of Denisovan ancestry in the world |
| Date: | 2021 |
| Source: | Current Biology |
| DOI: | 10.1016/j.cub.2021.07.022 |
| Abstract: | Multiple lines of evidence show that modern humans interbred with archaic Denisovans. Here, we report an account of shared demographic history between Australasians and Denisovans distinctively in Island Southeast Asia. Our analyses are based on ∼2.3 million genotypes from 118 ethnic groups of the Philippines, including 25 diverse self-identified Negrito populations, along with high-coverage genomes of Australopapuans and Ayta Magbukon Negritos. We show that Ayta Magbukon possess the highest level of Denisovan ancestry in the world—∼30%–40% greater than that of Australians and Papuans—consistent with an independent admixture event into Negritos from Denisovans. Together with the recently described Homo luzonensis, we suggest that there were multiple archaic species that inhabited the Philippines prior to the arrival of modern humans and that these archaic groups may have been genetically related. Altogether, our findings unveil a complex intertwined history of modern and archaic humans in the Asia-Pacific region, where distinct Islander Denisovan populations differentially admixed with incoming Australasians across multiple locations and at various points in time. |
| Volume: | 31 |
| Number: | 19 |
| Page Start: | 4219 |
| Page End: | 4230 |