Ref ID:	30246
Ref Type:	Journal Article
Authors:	Thurnham, D. I. Migasena, P. Vudhivai, Niyomsri Supawan, Venus
Title:	Riboflavin supplementation in a resettlement village in north-east Thailand
Date:	1972
Source:	British Journal of Nutrition
Notes:	A high prevalence of biochemical ariboflavinosis was shown to be present in the preschool children and a small group of adults in a village in north-east Thailand using an in vitro test based on erythrocyte glutathione reductase (EGR) activity. A riboflavin supplement of 10 mg/d was given to all subjects for 7 d. It was demonstrated that the riboflavin supplement cured the biochemical ariboflavinosis and the results supported the previous suggestion that a stimulation 20% of the in vitro EGR activity was a good indicator of ariboflavinosis. A dietary survey carried out on twenty preschool children during the experimental period showed riboflavin intake to be low, 0.18 ± 0.06 mg/Mcal. No glucose-6-phosphate dehydrogenase (G-6-PD)-deficient subjects were shown to be deficient in riboflavin by the in vitro test. The possibillity of using in vivo stimulation of EGR activity by riboflavin is discussed as a possible way of demonstrating ariboflavinosis in G-6-PD-deficient subjects.
Date Created:	4/17/2006
Volume:	28
Number:	1
Page Start:	91
Page End:	97